Recognizing the Differences: Autistic Burnout vs. Other Mental Health Conditions
- Esther Adams-Aharony

- Jul 19
- 2 min read

Autistic burnout shares several symptoms with depression, anxiety, and bipolar disorder—such as exhaustion, withdrawal, and cognitive difficulties—but it is a distinct experience rooted in the unique stressors faced by autistic individuals. Unlike these other conditions, autistic burnout arises primarily from chronic masking, sensory overload, and prolonged exposure to unsupportive environments.
It’s often misdiagnosed as depression, anxiety, or bipolar disorder, leading to treatment plans that miss the mark. While there’s some symptom overlap, the causes and required support systems are different.
Comparison: Autistic Burnout vs. Depression, Anxiety, and Bipolar Disorder
Feature
Autistic Burnout
Depression/Anxiety/Bipolar Disorder
Core Symptoms
Exhaustion, loss of skills, withdrawal, cognitive overload
Low mood, anxiety, mood swings, energy changes
Triggers
Chronic stress, masking, lack of support
Biological, psychological, and social factors
Misdiagnosis
Commonly mistaken for depression, anxiety, bipolar
Less likely to be confused with autistic burnout
Measurement Tools
AASPIRE Autistic Burnout Measure (ABM), ABM-NL
Standard psychiatric scales
Overlap and Distinctions
Overlap: Symptoms like fatigue, emotional exhaustion, and cognitive slowdowns are common in both autistic burnout and mood disorders.
Distinction: Autistic burnout is specifically linked to the autistic experience, including sensory processing challenges and the impact of camouflaging or masking behaviors.
Diagnosis: The development of specialized tools—such as the AASPIRE ABM—helps distinguish burnout from other mental health conditions, though continued research is needed to enhance accuracy .
Key Takeaway
While autistic burnout can resemble depression, anxiety, or bipolar disorder, it is not the same. Misidentification can lead to ineffective treatment. Recognizing autistic burnout as a distinct condition is essential for providing meaningful support and intervention.
References:
Arnold, S., Higgins, J., Weise, J., Desai, A., Pellicano, E., & Trollor, J. (2023). Confirming the nature of autistic burnout. Autism, 27(7), 1906–1918. https://doi.org/10.1177/13623613221147410
Arnold, S., Higgins, J., Weise, J., Desai, A., Pellicano, E., & Trollor, J. (2023). Towards the measurement of autistic burnout. Autism, 27(7), 1933–1948. https://doi.org/10.1177/13623613221147401
Mantzalas, J., Richdale, A., Li, X., & Dissanayake, C. (2024). Measuring and validating autistic burnout. Autism Research, 17(7), 1417–1449. https://doi.org/10.1002/aur.3129
Schoondermark, F., Spek, A., & Kiep, M. (2024). Evaluating an autistic burnout measurement in women. Journal of Autism and Developmental Disorders. https://doi.org/10.1007/s10803-024-06438-8



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