Understanding Complex PTSD and Its Specialized Treatment
- Esther Adams-Aharony

- Jul 19
- 4 min read

Complex PTSD (CPTSD) is a more severe and enduring form of PTSD, especially prevalent among individuals exposed to prolonged, repeated trauma—such as abuse, captivity, or chronic neglect. Beyond core PTSD symptoms (re-experiencing, avoidance, and hyperarousal), CPTSD includes disturbances in self-organization: affect dysregulation, negative self-concept, and difficulties in relationships. Treating CPTSD effectively requires comprehensive, trauma-focused psychological interventions tailored to these complexities.
Trauma-Focused Psychological Therapies
Cognitive Behavioral Therapy (CBT), Eye Movement Desensitization and Reprocessing (EMDR), and Prolonged Exposure (PE) consistently show moderate to large effectiveness in treating CPTSD. These interventions significantly reduce PTSD symptoms and help improve self-concept and interpersonal relations (Karatzias et al., 2019; Coventry et al., 2020; Cloitre, 2021; Bækkelund et al., 2022; Méndez et al., 2024; Watkins et al., 2018; Maercker et al., 2021). However, evidence supporting affect regulation improvements is more limited, suggesting the need for additional therapeutic components.
Multicomponent and Phase-Based Treatments
Because CPTSD includes affective and relational disturbances, experts recommend multicomponent treatments—integrating trauma-focused therapy with emotion regulation and interpersonal skills training (Coventry et al., 2020; Cloitre et al., 2011; Cloitre, 2021; Horesh & Lahav, 2024; Dyer & Corrigan, 2021; Maercker et al., 2021). These approaches are often structured in phases:
Stabilization – Building safety, trust, and initial self-regulation
Trauma processing – Directly addressing traumatic memories or experiences
Integration/rehabilitation – Consolidating gains, improving relationships, and rebuilding self-concept
While this phased model is widely endorsed, some clinicians argue for tailored flexibility—allowing certain patients to proceed without extensive stabilization if they are already capable of processing trauma (Jongh et al., 2016; Dyer & Corrigan, 2021).
Intensive and Remote Treatment Programs
Newer intensive treatment models—where trauma-focused therapies are delivered over shorter, concentrated periods—and remote/telehealth formats show strong, rapid symptom reduction with high safety and low dropout (Bongaerts et al., 2021; Bongaerts et al., 2022; Méndez et al., 2024). These approaches expand access for individuals in remote areas or who prefer accelerated programs.
Special Considerations and Pharmacological Adjuncts
Childhood-onset trauma and ongoing stressors often necessitate longer or more customized treatment plans (Karatzias et al., 2019; Cloitre, 2021; Dorrepaal et al., 2014; Maercker et al., 2021).
Medication, including antipsychotics or prazosin, can support symptom reduction but generally delivers smaller effects compared to psychological therapies (Coventry et al., 2020; Bisson & Olff, 2021; Sbarski & Akirav, 2020).
Final Thoughts
Overall, the strongest evidence supports trauma-focused, multicomponent psychological therapies, delivered in flexible or phased formats. While core PTSD symptoms respond well to CBT, EMDR, and PE, addressing the broader self-organization disturbances requires additional skill-building (e.g., emotion regulation). Intensive and remote treatment models are emerging as effective alternatives for people who need faster or more accessible options. Treatment must be individualized, especially for those with complex backgrounds involving childhood trauma or ongoing adversity.
References
Bækkelund, H., Endsjø, M., Peters, N., Babaii, A., & Egeland, K. (2022). Implementation of evidence-based treatment for PTSD in Norway: Clinical outcomes and impact of probable complex PTSD. European Journal of Psychotraumatology, 13. https://doi.org/10.1080/20008066.2022.2116827
Bisson, J., & Olff, M. (2021). Prevention and treatment of PTSD: The current evidence base. European Journal of Psychotraumatology, 12. https://doi.org/10.1080/20008198.2020.1824381
Bongaerts, H., Voorendonk, E., Van Minnen, A., Rozendaal, L., Telkamp, B., & De Jongh, A. (2022). Fully remote intensive trauma-focused treatment for PTSD and Complex PTSD. European Journal of Psychotraumatology, 13. https://doi.org/10.1080/20008066.2022.2103287
Bongaerts, H., Voorendonk, E., Van Minnen, A., & De Jongh, A. (2021). Safety and effectiveness of intensive treatment for complex PTSD delivered via home-based telehealth. European Journal of Psychotraumatology, 12. https://doi.org/10.1080/20008198.2020.1860346
Cloitre, M. (2021). Complex PTSD: Assessment and treatment. European Journal of Psychotraumatology, 12. https://doi.org/10.1080/20008198.2020.1866423
Cloitre, M., Courtois, C., Charuvastra, A., Carapezza, R., Stolbach, B., & Green, B. (2011). Treatment of complex PTSD: Results of the ISTSS expert clinician survey on best practices. Journal of Traumatic Stress, 24(6), 615–627. https://doi.org/10.1002/jts.20697
Coventry, P., Meader, N., Melton, H., Temple, M., Dale, H., Wright, K., Cloitre, M., Karatzias, T., Bisson, J., Roberts, N., Brown, J., Barbui, C., Churchill, R., Lovell, K., McMillan, D., & Gilbody, S. (2020). Psychological and pharmacological interventions for PTSD and comorbid mental health problems following complex traumatic events: Systematic review and component network meta-analysis. PLoS Medicine, 17. https://doi.org/10.1371/journal.pmed.1003262
Dorrepaal, E., Thomaes, K., Hoogendoorn, A., Veltman, D., Draijer, N., & Van Balkom, A. (2014). Evidence-based treatment for adult women with child abuse-related complex PTSD: A quantitative review. European Journal of Psychotraumatology, 5. https://doi.org/10.3402/ejpt.v5.23613
Dyer, K., & Corrigan, J. (2021). Psychological treatments for complex PTSD: A commentary on the clinical and empirical impasse dividing unimodal and phase-oriented therapy positions. Psychological Trauma: Theory, Research, Practice and Policy. https://doi.org/10.1037/tra0001080
Horesh, D., & Lahav, Y. (2024). When one tool is not enough: An integrative psychotherapeutic approach to treating complex PTSD. Journal of Clinical Psychology. https://doi.org/10.1002/jclp.23688
Jongh, A., Resick, P., Zoellner, L., Minnen, A., Lee, C., Monson, C., Foa, E., Wheeler, K., Broeke, E., Feeny, N., Rauch, S., Chard, K., Mueser, K., Sloan, D., Gaag, M., Rothbaum, B., Neuner, F., Roos, C., Hehenkamp, L., Rosner, R., & Bicanic, I. (2016). Critical analysis of the current treatment guidelines for complex PTSD in adults. Depression and Anxiety, 33. https://doi.org/10.1002/da.22469
Karatzias, T., Murphy, P., Cloitre, M., Bisson, J., Roberts, N., Shevlin, M., Hyland, P., Maercker, A., Ben‑Ezra, M., Coventry, P., Mason‑Roberts, S., Bradley, A., & Hutton, P. (2019). Psychological interventions for ICD‑11 complex PTSD symptoms: Systematic review and meta‑analysis. Psychological Medicine, 49, 1761–1775. https://doi.org/10.1017/S0033291719000436
Maercker, A., Cloitre, M., Bachem, R., Schlumpf, Y., Khoury, B., Hitchcock, C., & Bohus, M. (2021). Complex post‑traumatic stress disorder. The Lancet, 400, 60–72. https://doi.org/10.1017/9781108686976.018
Méndez, M., Nijdam, M., Ter Heide, F., Van Der Aa, N., & Olff, M. (2024). Response of patients with complex forms of PTSD to highly intensive trauma treatment: A clinical cohort study. Psychological Trauma: Theory, Research, Practice and Policy. https://doi.org/10.1037/tra0001747
Sbarski, B., & Akirav, I. (2020). Cannabinoids as therapeutics for PTSD. Pharmacology & Therapeutics, 107551. https://doi.org/10.1016/j.pharmthera.2020.107551
Watkins, L., Sprang, K., & Rothbaum, B. (2018). Treating PTSD: A review of evidence-based psychotherapy interventions. Frontiers in Behavioral Neuroscience, 12. https://doi.org/10.3389/fnbeh.2018.00258



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